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Biofactors. 2011 May-Jun;37(3):150-8. doi: 10.1002/biof.141. Epub 2011 Jun 14. Review.

Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.

Shull GE, Miller ML, Prasad V.

Cold Spring Harb Perspect Biol. 2011 May 1;3(5). pii: a004184. doi: 10.1101/cshperspect.a004184. Review.

The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus.

Vandecaetsbeek I, Vangheluwe P, Raeymaekers L, Wuytack F, Vanoevelen J.

J Invest Dermatol. 2009 Jun;129(6):1379-87. Epub 2008 Dec 4.

*Reevaluation of the normal epidermal calcium gradient, and analysis of calcium levels and ATP receptors in Hailey-Hailey and Darier epidermis.

Leinonen PT, Hägg PM, Peltonen S, Jouhilahti EM, Melkko J, Korkiamäki T, Oikarinen A, Peltonen J.

J Invest Dermatol. 2007 Aug;127(8):1973-9. Epub 2007 Mar 29.

*Involucrin expression is decreased in Hailey-Hailey keratinocytes owing to increased involucrin mRNA degradation.

Aberg KM, Racz E, Behne MJ, Mauro TM.

J Invest Dermatol. 2006 Nov;126(11):2370-6. Epub 2006 Jun 22. Review.

*Autosomal-dominant calcium ATPase disorders.

Szigeti R, Kellermayer R.

J Biol Chem. 2005 Mar 11;280(10):9467-73. Epub 2004 Dec 28.

*Deficiency of ATP2C1, a Golgi Ion Pump, Induces Secretory Pathway Defects in Endoplasmic Reticulum (ER)-associated Degradation and Sensitivity to ER Stress.

Ramos-Castaneda J, Park YN, Liu M, Hauser K, Rudolph H, Shull GE, Jonkman MF, Mori K, Ikeda S, Ogawa H, Arvan P. 

J Biol Chem. 2005 Jan 28; [Epub ahead of print]

*A novel isoform of the secretory pathway Ca2+, Mn2+-ATPase, hSPCA2, has unusual properties and is expressed in brain.

Xiang M, Mohamalawari D, Rao R. 

Biochim Biophys Acta. 2004 Dec 6;1742(1-3):103-12.

The Ca2+/Mn2+ pumps in the Golgi apparatus.

Van Baelen K, Dode L, Vanoevelen J, Callewaert G, De Smedt H, Missiaen L, Parys JB, Raeymaekers L, Wuytack F.

 Am J Med Genet. 2004 Nov 15;131C(1):20-31.

Calcium pump disorders of the skin.

Foggia L, Hovnanian A. 

Biochem Biophys Res Commun. 2004 Oct 1;322(4):1204-13.

SPCA1 pumps and Hailey-Hailey disease.

Missiaen L, Raeymaekers L, Dode L, Vanoevelen J, Van Baelen K, Parys JB, Callewaert G, De Smedt H, Segaert S, Wuytack F. 

Am J Physiol Cell Physiol. 2004 Sep;287(3):C580-9.

*Functional expression of heterologous proteins in yeast: insights into Ca2+ signaling and Ca2+-transporting ATPases.

Ton VK, Rao R.

Br J Dermatol. 2004 May;150(5):821-8.

*Calcium pumps and keratinocytes: lessons from Darier's disease and Hailey-Hailey disease.

Dhitavat J, Fairclough RJ, Hovnanian A, Burge SM. 

J Invest Dermatol. 2003 Oct;121(4):688-94.

*Human keratinocyte ATP2C1 localizes to the Golgi and controls Golgi Ca2+ stores.

Behne MJ, Tu CL, Aronchik I, Epstein E, Bench G, Bikle DD, Pozzan T, Mauro TM. 

J Invest Dermatol. 2003 Oct;121(4):681-7.

*Actin reorganization is abnormal and cellular ATP is decreased in Hailey-Hailey keratinocytes.

Aronchik I, Behne MJ, Leypoldt L, Crumrine D, Epstein E, Ikeda S, Mizoguchi M, Bench G, Pozzan T, Mauro T.

 Cell Calcium. 2003 Aug;34(2):157-62.

Similar Ca(2+)-signaling properties in keratinocytes and in COS-1 cells overexpressing the secretory-pathway Ca(2+)-ATPase SPCA1.

Callewaert G, Parys JB, De Smedt H, Raeymaekers L, Wuytack F, Vanoevelen J, Van Baelen K, Simoni A, Rizzuto R, Missiaen L. 

J Biol Chem. 2003 Jul 4;278(27):24721-30. Epub 2003 Apr 21.

*Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1).

Fairclough RJ, Dode L, Vanoevelen J, Andersen JP, Missiaen L, Raeymaekers L, Wuytack F, Hovnanian A. 

Pflugers Arch. 2003 May;446(2):148-53. Epub 2003 Feb 15.

*PMR1/SPCA Ca2+ pumps and the role of the Golgi apparatus as a Ca2+ store.

Wuytack F, Raeymaekers L, Missiaen L. 

Ann N Y Acad Sci. 2003 Apr;986:453-60.

Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.

Shull GE, Okunade G, Liu LH, Kozel P, Periasamy M, Lorenz JN, Prasad V.

 J Biol Chem. 2002 Feb 22;277(8):6422-7. Epub 2001 Dec 6.

Functional expression in yeast of the human secretory pathway Ca(2+), Mn(2+)-ATPase defective in Hailey-Hailey disease.

Ton VK, Mandal D, Vahadji C, Rao R. 

J Cutan Pathol. 2001 Jul;28(6):277-81.

*Upregulation of P-cadherin expression in the lesional skin of pemphigus, Hailey-Hailey disease and Darier's disease.

Hakuno M, Akiyama M, Shimizu H, Wheelock MJ, Nishikawa T. 

J Biol Chem. 2001 Apr 6;276(14):10683-91. Epub 2000 Dec 29.

*The Golgi PMR1 P-type ATPase of Caenorhabditis elegans. Identification of the gene and demonstration of calcium and manganese transport.

Van Baelen K, Vanoevelen J, Missiaen L, Raeymaekers L, Wuytack F.

Cell Calcium. 2000 Jul;28(1):1-21.

Abnormal intracellular ca(2+)homeostasis and disease.

Missiaen L, Robberecht W, van den Bosch L, Callewaert G, Parys JB, Wuytack F, Raeymaekers L, Nilius B, Eggermont J, De Smedt H.

Hum Mol Genet. 2000 Apr 12;9(7):1131-40.

*Hailey-Hailey disease is caused by mutations in ATP2C1 encoding a novel Ca(2+) pump.

Sudbrak R, Brown J, Dobson-Stone C, Carter S, Ramser J, White J, Healy E, Dissanayake M, Larregue M, Perrussel M, Lehrach H, Munro CS, Strachan T, Burge S, Hovnanian A, Monaco AP. 

Nat Genet. 2000 Jan;24(1):61-5.

*Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease.

Hu Z, Bonifas JM, Beech J, Bench G, Shigihara T, Ogawa H, Ikeda S, Mauro T, Epstein EH Jr. 

Br J Dermatol. 1999 Aug;141(2):224-30.

*Internalization of gap junctions in benign familial pemphigus (Hailey-Hailey disease) and keratosis follicularis (Darier's disease).

Haftek M, Kowalewski C, Mesnil M, Blaszczyk M, Schmitt D.

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